Mazetol SR 400 Tablet is an anti-epileptic medicine used to treat epilepsy. It helps prevent certain types of seizures (fits). It is also prescribed for a painful condition of the face, head, and neck known as trigeminal neuralgia and diabetes-related nerve pain (diabetic neuropathy). Mazetol SR 400 Tablet must be taken with or without food, but take it at the same time every day. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. It may be increased gradually. Many other medicines can interfere with this medicine so tell your doctor about all the medicines you are taking to make sure it is safe. You can take this medicine with or without food but take it regularly at the same time each day to get the maximum benefit. It is important to take this medicine for as long as you are advised, even if you feel well. Missing even a single dose may trigger a seizure and, if you stop taking it abruptly, your condition may get worse. The most common side effects of this medicine include nausea, vomiting, feeling dizzy, tired or drowsy, unsteadiness (balance disorder), constipation, dry mouth, and itching. Some people may develop blurring of vision and slurred speech. Most of the side effects are not serious. However, let your doctor know straight away if you notice a skin rash or if your mood becomes depressed or if you develop any thoughts about harming yourself. Before taking Mazetol SR 400 Tablet, tell your doctor if you have any heart problems, kidney or liver disease, difficulty in urinating, or any mental illness like depression. These conditions may affect your treatment. You may be advised some blood tests (eg. CBC) before starting treatment and then periodically thereafter, to monitor your progress. In Epilepsy/Seizures Mazetol SR 400 Tablet works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure. In Trigeminal neuralgia Mazetol SR 400 Tablet can relieve nerve pain by decreasing nerve impulses which cause the pain (in the trigeminal nerve in your face). It is effective in treating this condition although other medications may also be used. It will enable you to carry out certain daily activities like shaving, putting on make-up, eating, drinking, and brushing your teeth with some freedom from the worry and pain that trigeminal neuralgia can cause. It is not associated with any physical or psychological dependence (addiction) but should not be stopped suddenly. In Diabetic nerve pain Mazetol SR 400 Tablet relieves nerve pain by decreasing nerve impulses which cause the pain. If the pain is reduced you will feel more comfortable going about your daily life, but you should continue with all other diabetes medicines as prescribed. This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective.